First in Japan　to have submitted a notification of Foods with Function Claims for liver function with a new ingredient “Garcinol derived from Garcinia indica”.

Toyo Shinyaku Co., Ltd. (Head Office: Fukuoka City, Fukuoka Prefecture; Headquarters: Tosu City, Saga Prefecture; President: Toshimitsu Hattori) has submitted a notification for Foods with Function Claims for “Garcinol derived from Garcinia indica” as a functional ingredient with the indication “reduces slightly elevated blood ALT and AST levels in the normal range. The notification was published on January 4th, 2024.

*Blood ALT and AST levels are one of the indicators of liver health.

TOYO SHINYAKU submitted a notification to the Consumer Affairs Agency for “Garcinia indica Tablet L” containing “Garcinol derived from Garcinia indica“, a characteristic ingredient of Garcinia indica, as a Foods with Function Claims, and it was made public as of January 4th, 2024. (Notification No.: I909) Garcinol derived from Garcinia indica is a new functional ingredient that has never been reported before.

We prepared a systematic review (SR) based on human study data conducted by our company and submitted a notification with the indication of “reduces slightly elevated blood ALT and AST levels in the healthy range.

Notification details
Product Name : Garcinia indica Tablet L
Notification No. : I909
Amount of functional ingredient contained in each recommended daily intake :
［Functional Ingredient] Garcinol derived from Garcinia indica
［Content] 18.0 mg/day
Submitted Claim: This product contains garcinol from Garcinia indica. Garcinol derived from Garcinia indica has been reported to have the ability to lower blood ALT and AST levels, which are slightly elevated in healthy people in the normal range. Blood ALT and AST levels are one of the indicators of liver health.

What is “Garcinol derived from Garcinia indica“? The Garcinia indica is a member of the Dipterocarpaceae family that grows wild in India. Its fruit is used as a spice in curries and other dishes, and has long been used in Ayurveda, a traditional Indian medicine, for its various health benefits. Garcinol derived from Garcinia indica is extracted from the rind of Garcinia indica. Garcinol derived from Garcinia indica has an anti-inflammatory effect and is believed to help protect the liver, which is important to take care of on a daily basis, and improves liver function by suppressing liver inflammation caused by daily lifestyle habits such as drinking, smoking, and stress.

What is the system of “Foods with Functional Claims”? Until March 2015, the ability to display functionality in food labeling was limited to Food for Specified Health Uses (FOSHU) approved by the government and Food with Nutrient Function Claims (FNFC) that conform to standards and criteria specified by the government. These systems remain in place today. In addition to these categories, a new type of food with health claims, called Foods with Function Claims, was introduced in April 2015. Food business operators* can make function claims on food labels when they submit to the Secretary-General of the Consumer Affairs Agency the necessary information including scientific evidence on food safety and effectiveness in accordance with the rules prescribed by the law before marketing the product. *Food business operator refers to food importers, food manufacturers, food producers and food retailers.

TOYO SHINYAKU will continue to discover new possibilities of materials and provide high value-added products as an ODEM (ODM & OEM) manufacturer of health foods and cosmetics to contribute to the “health” and “beauty” of as many people as possible.