Submitted a notification of Foods with Function Claims for “procyanidins B1 and B3 derived from pine bark” that “maintains skin elasticity by maintaining peripheral blood flow and is beneficial to skin health”.

Toyo Shinyaku Co., Ltd. (Head Office: Fukuoka City, Fukuoka Prefecture; Headquarters: Tosu City, Saga Prefecture; President: Toshimitsu Hattori) has submitted a notification of “Flavan Tablet C2E2 ” for Foods with Function Claims with “procyanidins B1 and B3 derived from pine bark” as the functional ingredients, with the indication “maintains skin elasticity by maintaining peripheral blood flow and is beneficial to skin health “. “Flavan Tablet C2E2” was filed and published on February 5th, 2024.

As a product of Foods with Function Claims claiming “procyanidins B1 and B3 derived from pine bark” as the functional ingredient, it has been claimed to “lower LDL cholesterol levels and total cholesterol levels,” “help maintain vascular suppleness (flexibility), which declines with aging (degree of vascular dilation after vascular tightening),” and “help maintain skin elasticity and skin health”. It has a track record of being filed with the labeling that it “helps maintain elasticity of the skin and skin health”. The new notification was submitted to the Japanese Ministry of Health, Labour and Welfare with a new claim that “procyanidins B1 and B3 derived from pine bark” help maintain skin elasticity by improving peripheral blood flow, and thus “help maintain skin elasticity and skin health by maintaining peripheral blood flow”. This will enable the product development of Foods with a Function Claims that includes “maintenance of peripheral blood flow” as the mechanism of action in the labeling of “procyanidins B1 and B3 derived from pine bark” for the skin.

Notification details
Product Name : Flavan Tablet C2E2
Notification No.: I1037
Functional Ingredients : Procyanidins B1 and B3 derived from pine bark
Submitted Claim: This product contains procyanidins B1 and B3 derived from pine bark. This product contains procyanidins B1 and B3 derived from pine bark. This product containsprocyanidins B1 and B3 derived from pine bark. Procyanidins B1 and B3 derived from pine bark have been reported to help maintain skin elasticity and skin health by maintaining peripheral blood flow. Recommended daily intake : 2 capsules (2.4 mg of procyanidins B1 and B3 derived from pine bark)

What are procyanidins B1 and B3 derived from pine bark? Procyanidins B1 and B3 derived from pine bark are the characteristic ingredients of Flavangenol®, a proprietary material of TOYO SHINYAKU. Flavangenol® is extracted from the bark of French maritime pine trees planted in Western Europe. It is rich in polyphenols and has been shown to exhibit various physiological activities, including antioxidant effects. TOYO SHINYAKU has been conducting research on the functionality of Flavangenol®, and has confirmed various effects such as improvement of skin brightness, blood flow, and platelet aggregation, in addition to cholesterol reduction, improvement of vascular endothelial function, and maintenance of skin elasticity.

What is the system of “Foods with Functional Claims”? Until March 2015, the ability to display functionality in food labeling was limited to Food for Specified Health Uses (FOSHU) approved by the government and Food with Nutrient Function Claims (FNFC) that conform to standards and criteria specified by the government. These systems remain in place today. In addition to these categories, a new type of food with health claims, called Foods with Function Claims, was introduced in April 2015. Food business operators* can make function claims on food labels when they submit to the Secretary-General of the Consumer Affairs Agency the necessary information including scientific evidence on food safety and effectiveness in accordance with the rules prescribed by the law before marketing the product. *Food business operator refers to food importers, food manufacturers, food producers and food retailers.

TOYO SHINYAKU will continue to discover new possibilities of materials and provide high value-added products as an ODEM (ODM & OEM) manufacturer of health foods and cosmetics to contribute to the “health” and “beauty” of as many people as possible.